SHROOM4

(redirected from KIAA1202)

SHROOM4

A gene on chromosome Xp11.22 that encodes a protein which may regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II; it thus plays a key role in development.

Molecular pathology
Defects of SHROOM4 cause mental retardation syndromic X-linked Stocco dos Santos type; several SHROOM4 translocations cause X-linked mental retardation.
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