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A gene on chromosome 8q22.1 that encodes a member of the bone morphogenetic protein (BMP) family of secreted signalling molecules. GDF6 is required for normal formation of specific bones and joints in the limbs, skull and axial skeleton.

Molecular pathology
GDF6 mutations result in colobomata (congenital defects in ocular development) and Klippel-Feil syndrome (a congenital disorder of spinal segmentation).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
But protests saw KFS and Kenya Maritime Authority launch investigations into the incident which could have resulte into a disaster similar to Mtongwe 1994 ferry disaster which killed more than 200 commuters.
Australian consumer research into home loans (prior to the introduction of KFS) corroborates the international experience that the length, complexity, and design layout of home loan contracts hampers consumer understanding of the agreement.
In order to be admitted to KFS, a student needs to have at least one parent from a foreign country, or to have lived abroad for at least three years.
KFS is supposed to facilitate community participation in forest management and collaborative management in general by including all relevant stakeholders in decision-making processes.
'This festival would not have been possible without the presence of the foreign delegates, the culture department of the Sindh government, ministry of information of the federal government, founding members of KFS, the entertainment fraternity and everyone who trusted our vision and supported us.
They are managed by KFS, with some areas managed as national parks and game reserves by the Kenya Wildlife Service (KWS), while a smaller area falls under the authority of local governments (GATSBY Charitable Foundation 2014).
The classic cervical vertebral abnormalities of KFS are well known and associated with derangements within the signaling pathways during paraxial mesoderm differentiation and somite development [12].
Having successfully completed projects serving UK-based manufacturers KFS Group already gained an excellent reputation on the UK market.
The KFS brand has been in business for more than 25 years.
The classic clinical triad of Klippel-Feil syndrome (KFS) -short neck, restricted neck mobility, and low dorsal hairline- is the result of congenital synostosis of a variable number of cervical vertebrae.
The central pathological wound healing response of keloid scarring is composed of a high density of mesenchymal cells called keloid fibroblasts (KFs) [9, 10].
The aqueous solution of petroleum ether leaf extract (KFL) and chloroform stem extract (KFS) of Kedrostis foetidissima was treated with varying concentrations of silver nitrate (3 mM) solution in the ratios 5:1, 5:2, 5:3, 5:4, and 5: 5 under room temperature, higher temperature, and sonication.