KDM4A

KDM4A

A gene on chromosome 1p34.1 that encodes lysine-specific demethylase 4A, which demethylates histone H3; it generates formaldehyde and succinate and acts as a transcription repressor.
References in periodicals archive ?
They found two demethylases, KDM4A and KDM4C, were produced in abundance during the transformation.
Depleting KDM4A alone had a greater effect than did KDM4C, suggesting that it plays an earlier role in blood vessel cell development.
Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells," Stem Cell Reports, 2015; DOI: 10.