KDM3B | definition of KDM3B by Medical dictionary
KDM3B A gene on chromosome 2p11.2 that encodes lysine-specific demethylase 3B, which demethylates histone H3 and thus plays a central role in histone code. The demethylation reaction generates formaldehyde and succinate. KDM3B may have tumour suppressor activity.
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References in periodicals archive
Histone 3 lysine 9 methylation was regulated by histone methyltransferase G9a, SUV39H1, SUV39H2, and histone demethylase LSD1, KDM3A, KDM3B
, KDM4A, KDM4B, and KDM4C [20, 21].
The TEPs address protein targets in cancer - HDAC6, SETDB1, PHIP, KDM3B
, KDM4D, RECQL5, and malaria - PfBDP4B.