KDM1A

(redirected from KDM1)

KDM1A

A gene on chromosome 1p36.12 that encodes a demethylase which acts on histone H3 as a coactivator or a co-repressor, depending on the context.
References in periodicals archive ?
H3K4 is demethylated by the KDM1 family (LSD1 and AOF1), the KDM2 family (FBXL10), and the KDM5 family (JARID1A, JARID1B, JARID1C, and JARID1D) as well as JARID2 and NO66.
H3K9 is demethylated by the KDM1 family (LSD1), the KDM3 family (JMJD1A and JMJD1B), and the KDM4 family (JMJD2A, JMJD2B, JMJD2C, and JMJD2D) as well as JMJD1C, PHF8, and JHDM1D.
Krishnan et al., "KDM1 is a novel therapeutic target for the treatment of gliomas," Oncotarget, vol.
The frame for building the indicators K, D, KD, KDM1, KDP1 follows the methodology implemented in Trifan (2010).