motif

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motif

(mō-tēf′)
n.
1.
a. A recurrent thematic element in an artistic or literary work.
b. A dominant theme or central idea.
2. Music A short rhythmic or melodic passage that is repeated or evoked in various parts of a composition.
3. A repeated figure or design in architecture or decoration.
4. A recurrent pattern either of molecular sequence, usually of nucleotides or amino acids in proteins, or of molecular structure that usually corresponds to specific biological activity.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

motif

A short, conserved cluster of amino acids or nucleotides which share structural and usually functional similarity on a macromolecule; a 3-dimensional structure of gene product/protein with known or implied functions, often inferred from the cDNA sequence.

Protein motifs
DNA binding, leucine zipper, membrane spanning, zinc finger.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

motif

(of a PROTEIN) a specific combination of SECONDARY STRUCTURES exhibiting a characteristic three-dimensional structure and often associated with a particular function. For example, the coiled-coil motif, comprising of two or more helices wound around each other. This is found in the GLYCOPROTEIN of EBOLA VIRUS and has a role in entry of the virus into host cells. Also the ZINC FINGER which comprises of an α helix and two β strands forming a finger-like structure held together by a zinc ion.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Patient discussion about motif

Q. What other illnesses are similar to asthma? I am 45 years old. My doctor suspects I might have adult asthma but there has yet been a final diagnosis made. What other problems might this be?

A. Before diagnosing someone as asthmatic, alternative possibilities should be considered. A clinician taking a history should check whether the patient is using any known bronchoconstrictors (substances that cause narrowing of the airways, e.g., certain anti-inflammatory agents or beta-blockers). Chronic obstructive pulmonary disease, which closely resembles asthma, is correlated with more exposure to cigarette smoke, an older patient, and decreased likelihood of family history of atopy. Your physician should examine these possibilities as well before diagnosing.

More discussions about motif
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References in periodicals archive ?
This study utilized the perceived benefits and perceived self-efficacy factors of the behavior-specific cognition and affect component of the HPM to evaluate and compare the clinical outcomes of participants and non-participants of a Medicare KDE program.
KDE transforms a dot pattern into a continuous surface, providing a more useful representation of pollution and asthma cases distributions, allowing for easier detection of possible pollution hotspots and its association with asthma cases.
In the results of three different noise ratio tests, the cleaning time of WDE should be less than KDE. Comprehensive comparison shows that, in premise of ensuring the accuracy of cleaning, the time cost of WDE is less than KDE, especially when noise data make up higher proportion in RFID data cleaning.
[16], kde je jako alternativ ni ucelovy funkcional uveden vztah pro kumulativni spotrebu na jednoho obyvatele uvazovaneho ekonomickeho celku.
Leveraging the KDE application development framework a great number of applications have been built for the K Desktop Environment.
Customers will use smart cards designed by KDE that will instantly record transactions on computers supplied by IVS.
The graphical desktop environment is KDE, and you can work with its windows-like screens open the command-line level and learn Linux.
Note: We will have an Internet assignment that will include a visit to the KDE Website.
The Kentucky Department of Education (KDE) was responsible for operationalizing KERA and determining the success of schools in attaining its goals.
The target, which is based in Tucson, Arizona, operates via its subsidiaries KD Engineering (KDE) and Metcon Research.