KCNE4

KCNE4

A gene on chromosome 2q36.1 that encodes a beta subunit of the voltage-gated, isk-related potassium channel subfamily. This type-I membrane protein assembles with a potassium channel alpha subunit to modulate gating kinetics and stabilise the multimeric complex. It is primarily expressed in the embryo and adult uterus.
References in periodicals archive ?
The KCNE gene family, including KCNE1, KCNE2, KCNE3, KCNE4, and KCNE5 genes, encodes protein Mink and Mink-related peptide (MIRP1-4) protein molecules that form [beta]-subunit to constitute the functional potassium channel [28].
As shown in Figure 2(a), we first found that 199 genes were overlapped among CDH1- and CDH2-enriched genes; after CDH2-, CDH4-, CDH6-, and CDH17-enriched genes were considered together, we generated a refined list of CDH2/4/6/17-associated genes (101 genes) (Figure 2(a), Supplementary Table S3), which were all contained in CDH1/2-enriched genes except 2 genes (KCNE4 and ZDHHC1).