KCNE4 | definition of KCNE4 by Medical dictionary
KCNE4 A gene on chromosome 2q36.1 that encodes a beta subunit of the voltage-gated, isk-related potassium channel subfamily. This type-I membrane protein assembles with a potassium channel alpha subunit to modulate gating kinetics and stabilise the multimeric complex. It is primarily expressed in the embryo and adult uterus.
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References in periodicals archive
The KCNE gene family, including KCNE1, KCNE2, KCNE3, KCNE4
, and KCNE5 genes, encodes protein Mink and Mink-related peptide (MIRP1-4) protein molecules that form [beta]-subunit to constitute the functional potassium channel .
As shown in Figure 2(a), we first found that 199 genes were overlapped among CDH1- and CDH2-enriched genes; after CDH2-, CDH4-, CDH6-, and CDH17-enriched genes were considered together, we generated a refined list of CDH2/4/6/17-associated genes (101 genes) (Figure 2(a), Supplementary Table S3), which were all contained in CDH1/2-enriched genes except 2 genes (KCNE4