CDH6

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CDH6

A gene on chromosome 5p13.3 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH6 is a so-called type-II (atypical) cadherin—which lacks a HAV cell adhesion recognition sequence specific to type-I cadherins—and may play a role in kidney, endometrial and placenta development. It is highly expressed in the brain, cerebellum and kidneys.

Molecular pathology
Decreased CDH6 expression is linked to tumour growth and metastasis.
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References in periodicals archive ?
KCAD, headquartered in Aberdeen, has also won a new contract for one of its 2000 HP land rigs to drill four wells in southern Russia.
Simon Drew, president of KCAD's land drilling business, said: "Our fleet in Russia continues to see high utilisation.
KCAD's drilling rig and oilfield equipment manufacturer, Bentec, also has a substantial manufacturing facility located in Nizwa, which operates as IDTEC.
In addition to our 17 land rigs in Russia, KCAD is the drilling contractor on three platforms offshore Sakhalin Island.