KAT5

KAT5

A gene on chromosome 11q13 that encodes a catalytic subunit of the NuA4 histone acetyltransferase complex (NuA4 HAC) involved in transcriptional activation of genes, principally by acetylating nucleosomal histones H4 and H2A. The NuA4 HAC may be required for activating transcription programmes of oncogene and proto-oncogene mediated growth induction, tumour suppressor-mediated growth arrest/replicative senescence, apoptosis, and DNA repair. Post-translational modifications include sumoylation, phosphorylation, ubiquination and autoacetylation.
References in periodicals archive ?
KAT5 through KAT7, added to the survey in June 2006, were designed to indicate more specifically how many persons not living at their former addresses had returned to them for more than a short period, and to get a sense of how many "normal movers" (people who moved for reasons other than Katrina) the questions may have been picking up.
month --day KAT5 Did you move back, even temporarily, to the address you had prior to Hurricane Katrina?