PROKR2

(redirected from KAL3)

PROKR2

A gene on chromosome 20p12.3 that encodes the G protein-coupled receptor for prokineticin 2, one of a family of proteins that promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. PROKR2 activation mobilises calcium, stimulates phosphoinositide turnover and activates p44/p42 mitogen-activated protein kinase.
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References in periodicals archive ?
(2) Apart from KAL1 (Xp 22.3), the genes responsible for the KS phenotype are the KAL2 [fibroblast growth factor receptor 1] (FGFR1) gene (10%) and the KAL4 [Prokinetecin receptor 2] (PROKR2) and KAL3 [Prokinetecin 2] (PROK2) (9%) genes.