KRAS

(redirected from K-RAS2B)

KRAS

A Kirsten ras oncogene homolog from the mammalian ras gene family on chromosome 12p12.1, which encodes a small GTPase in which a single amino acid substitution results in a transforming protein.

Molecular pathology
The KRAS transforming protein has been linked to various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas, colorectal carcinoma, acute myelogenous leukaemia, juvenile myelomonocytic leukaemia, gastric cancer, pilocytic astrocytoma, Noonan syndrome type 3, and cardiofaciocutaneous syndrome
References in classic literature ?
The life lies low in a Mingo, and humanity teaches us to make a quick end to the sarpents.
We are certainly on an island, for I went as high as I could this morning, and saw the sea reaching all round it to the horizon; it lies low, but towards the middle I saw smoke rising from out of a thick forest of trees.