TYK2

(redirected from JTK1)

TYK2

A gene on chromosome 19p13.2 that encodes a non-receptor protein tyrosine kinase, which phosphorylates IFN-alpha/beta receptor alpha chains and may be involved in intracellular signal transduction by initiating type-I IFN signalling.

Molecular pathology
TYK2 defects cause protein-tyrosine kinase 2 deficiency.