SPAG9

(redirected from JNK interacting protein)

SPAG9

A gene on chromosome 17q21.33 that encodes sperm-associated antigen 9, a member of the JNK-interacting protein (JIP) group of scaffold proteins, which selectively mediates JNK signalling by aggregating specific components of the MAPK cascade to form a functional JNK-signalling module.
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References in periodicals archive ?
The mitogen activated protein kinase (MAPK) 8 interacting protein 1 (MAPK8IP1) gene encodes islet brain 1 (IB1) also termed as JNK interacting protein 1, a protein that tethers kinases of the JNK pathway.