KDM3B

(redirected from JMJD1B)

KDM3B

A gene on chromosome 2p11.2 that encodes lysine-specific demethylase 3B, which demethylates histone H3 and thus plays a central role in histone code. The demethylation reaction generates formaldehyde and succinate. KDM3B may have tumour suppressor activity.
References in periodicals archive ?
H3K9 is demethylated by the KDM1 family (LSD1), the KDM3 family (JMJD1A and JMJD1B), and the KDM4 family (JMJD2A, JMJD2B, JMJD2C, and JMJD2D) as well as JMJD1C, PHF8, and JHDM1D.