JARID2

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JARID2

A gene on chromosome 6p24-p23 that encodes an ortholog of the mouse jumonji gene, which encodes a nuclear protein essential for mouse embryogenesis. JARID2 is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion and haematopoiesis, modulating histone methyltransferase activity and recruiting histone methyltransferase complexes to their target genes; it downregulates cell proliferation signalling pathways. During embryogenesis, it is primarily expressed in neurons, especially in dorsal root ganglion cells. It interacts with GATA4, NKX2-5, RB1, SUZ12 and ZNF496.
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References in periodicals archive ?
In the United States, JMJ developed the Frisco Bridges in Frisco, Texas, and the West World Development in Palm Springs, Calif.
The Qatari Business Women Association ( QBWA) has signed a partnership agreement with JMJ Associates, a global management consultancy specialising in developing high-performing organisations and project cultures.
"We look forward to a successful partnership with JMJ and to continuing to expand throughout India."
Finally, he gave "ecclesiological guidelines" based on missionary discipleship as a "journey" and "a vocation: a call and an invitation." It occurs "today" but always "in tension" because "there is no such thing as static missionary discipleship." The focus of missionary discipleship is "not in the centre but at the periphery." Disciples are sent to "existential peripheries." Echoing his example during the JMJ and referring to the Aparecida Document, he reminded the bishops of the pastoral attitudes necessary for missionary discipleship: "nearness and encounter." He called for an incarnational "revolution of tenderness" and pleaded with the bishops to shepherd not with the authority or behavior of "princes" but with mercy and patience.
Nessa perspectiva, consideraremos a JMJ Rio 2013--megaevento religioso turistico internacional--como exemplo empirico para o desenvolvimento desta reflexao, isto e, uma introducao teorica acerca das interfaces entre geografia, turismo, religiao e relacao internacionais.
Soaking up JMJ's advice, Scratch says the most vital thing he learned was to read the crowd and relate his show to them.
21 October 2013 - UK private equity firm 3i Group plc (LON:III) said today that it would invest in a 55% stake in US-based management consultancy JMJ Associates LLC together with the target's management.
He is also a managing director for JMJ Summit Services where he provides professional advisement services for technology based companies and performs utility industry research.
Beerschot went bust but Country Bus, along with Nairobi City Stars, JMJ Academy and AFC Leopards, are all desperate for the sum of almost PS600,000 they believe is due to them.
In 2008 AI enlisted the services of consultancy JMJ Associates, which helped to establish further protocols designed to keep safety top-of-mind.
Cinq mois apres son intronisation, le Pape Francois entamait hier lundi son premier deplacement a l'etranger dans son continent d'origine, l'Amerique latine, a l'occasion des Journees mondiales de la Jeunesse (JMJ), evenement biennal qui se deroule cette fois-ci au Bresil.