HFE2(redirected from JH)
Also found in: Acronyms.
Abbreviation for hemochromatosis type 2.
HFE2A gene on chromosome 1q21.1 that encodes a protein which may be involved in iron metabolism, by activating the hepcidin signalling pathway, modulating hepcidin expression or acting as the hepcidin cell receptor.
HFE2 mutations are linked to hemochromatosis type 2A—e.g., juvenile hemochromatosis.