(Ashley et al., 2011; Abbing et al., 2004) To deliver Paclitaxel, a JC polyomavirus
VLP system was also synthesized which encapsulates the coupled drug with cyclodextrins as hydrophobic pockets through disulfide bonds inside the VLPs and has capable of glutathione (GSH)- triggered release of drug molecules.
Results of PCRs for AFB, cytomegalovirus, and JC polyomavirus
On culturing JC polyomavirus
, deletions in the viral genome commonly arise (37), and these deletions often involve the T antigen (38).
The human BK polyomavirus (BKPyV) and JC polyomavirus
(JCPyV) are ubiquitous pathogens .
(119,121) Many of the available antibodies react with epitopes common to SV-40, BK polyomavirus, and JC polyomavirus
and thus can be applied to diagnosis of nephropathy (most often BK), cystitis (BK and some JC), and progressive multifocal leukoencephalopathy (generally JC).
Gallia et al., "Cooperative action of cellular proteins YB-1 and Pura with the tumor antigen of the human JC polyomavirus
determines their interaction with the viral lytic control element," Proceedings of the National Academy of Sciences of the United States of America, vol.
Infection with BK polyomavirus (BKPyV) or JC polyomavirus
causes substantial illness and death in immunocompromised populations, including transplant recipients and HIV patients (1).
Gran, "Atypical progressive multifocal leukoencephalopathy associated with an unusual JC polyomavirus
mutation," Archives of Neurology, vol.
There are 5 human polyomaviruses: BK polyomavirus, JC polyomavirus
, KI (Karolinska Institute) polyomavirus, WU (Washington University) polyomavirus, and Merkel cell virus.
was also detected in the urine but not in the blood.
Khalili, "Transcriptional regulation of human JC polyomavirus
promoters by cellular proteins YB-1 and Pur a in glial cells," Journal of Virology, vol.
BK polyomavirus (BKPyV) has been associated with nephropathy in renal transplant recipients and JC polyomavirus
(JCPyV) with progressive multifocal leukoencephalopathy in immunocompromised persons (2,3).