JAM3
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JAM3
A gene on chromosome 11q25 that encodes a member of the immunoglobulin superfamily, which localises in the tight junctions between high endothelial cells of lymph nodes and acts as a counter-receptor for ITGAM, mediating leukocyte-platelet interactions. It is involved in regulating transepithelial migration of polymorphonuclear neutrophils.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.