itai-itai disease

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i·tai-·i·tai dis·ease

a form of cadmium poisoning described in some Japanese people, characterized by renal tubular dysfunction, osteomalacia, pseudofractures, and anemia, caused by ingestion of contaminated shellfish or other sources containing cadmium.

A form of renal osteodystrophy—osteomalacia with marked bone pain and painful fractures—described in multiparous Japanese women due to cadmium accumulation in bone, caused by industrial pollutants

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cadmium poisoning

References in periodicals archive ?

The osteomalacia observed in Itai-itai disease would have occurred as a consequence of Cd-induced damage to the renal cortex, which probably hampered the occurrence of the second hydroxylation of vitamin D in the affected cells [28].

A Greater Capacity of Metallothionein Synthesis: Would it be Sufficient as Explanation for the Absence of Pathological Effects in Marine Mammals with Extremely High Cd Concentrations? A Review

They also pose a number of health hazards to humans such as Cd intake can lead to itai-itai disease, mercury accumulation may cause minimata disease and As intake through contaminated drinking water can cause poisoning [5].

Perilous Effects of Heavy Metals Contamination on Human Health

Itai-Itai disease, which affected thousands of people in Japan and even many lead to death, was caused by Cd (Baby et al., 2010).

Short Communication - Lead and Cadmium Concentration in the Human Blood Samples of Muzaffarabad, AJK, Pakistan

In the mid of 1950s a disease named itai-itai was reported in Japan.

Silicon application can minimize cadmium accumulation in wheat

In contaminated regions of Japan the chronic exposure of humans to Cd resulted in the occurrence of an epidemic of osteomalacia (Itai-Itai when concentration of Cd reached or exceeded 200 g/g

Effect of Iron Plaque and Selenium on Cadmium Uptake and Translocation in Rice Seedlings (Oryza sativa) Grown in Solution Culture

In Japan, excessive cadmium in the diets of some older women has caused "itai-itai"--or "ouch-ouch" disease.

Chemical quandary: chemicals are essential to our way of life, but who's ensuring their safe use?

Combined effects of estrogen deficiency and cadmium exposure on calcified hard tissues: Animal model relating to itai-itai disease in postmenopausal women Mitsuo Kakei, Toshiro Sakae and Masayoshi Yoshikawa Communicated by Tatsuo Suda, M.J.A.

Proceedings at the 1070th General Meeting

Itai-itai (ouch-ouch) disease caused by cadmium (Cd) exposure is considered a type of osteomalacia, and is characterized by increased osteoid formation, with low-grade bone mineralization.

Combined effects of estrogen deficiency and cadmium exposure on calcified hard tissues: animal model relating to itai-itai disease in postmenopausal women

Man being at the top of many food chains is highly vulnerable as in the cases of Cd and Hg poisoning (Itai-itai and Rheumatic diseases) in the Jintsu River and Minamata, Japan [11,20].

Assessment level of heavy metal in prawns (Macrobrachium Macrobrachion) and water from Epe Lagoon

Long-term exposure to high-dose cadmium causes Itai-itai disease.

Cadmium, environmental exposure, and health outcomes/O cadmio, a exposicao ambiental ao cadmio e as consequencias para a saude

O caso mais conhecido de intoxicacao por cadmio por meio dos alimentos ocorreu nas margens do rio Jintsu, na cidade de Funchi-machi, no Japao, logo apos a II Guerra Mundial: um grande numero de pessoas, plantadores de arroz e pescadores foram acometidos de dores reumaticas e mialgias, acompanhadas de deformidades osseas e disturbios renais, o que se denominou doenca Itai-Itai (ouch-ouch) (KAZUYA, 2000).

Assessment of heavy metal levels in percolated liquid from sanitary landfill in Paranavai, Parana State, Brazil/Avaliacao dos niveis de metais pesados em efluente liquido percolado do aterro sanitario de Paranavai, Estado do Parana, Brasil

The typical patient with itai-itai disease was reported to be a middle aged postmenopausal multiparous woman who had lumbar pains, leg myalgia, and ducklike gait.