isotopic tracer

(redirected from Isotopic labeling)
Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to Isotopic labeling: radiolabeled

isotopic tracer

[ī′sətop′ik]
Etymology: Gk, isos + topos, place; Fr, tracer, to track
an isotope or mixture of isotopes of an element incorporated into a sample to permit observation of the course of the element through a chemical, physical, or biological process. The observations may be made by measuring the radioactivity or the abundance of the isotope.
References in periodicals archive ?
announced today a collaboration to use KineMed's isotopic labeling and dynamic proteomics platform to investigate the turnover rates of huntingtin protein, a mutant form of which plays a central role in the pathogenesis of Huntington's disease (HD).
Fanara will focus on KineMed's use of non-radioactive isotopic labeling to compare changes in the kinetics of biochemical processes between healthy and diseased states, thereby identifying pathways that are causal in pathogenesis.
These include the development of isotopic labeling, sample preparation, data analysis, and information visualization techniques for liquid chromatography/mass spectrometry data.
This discovery was made possible by KineMed's proprietary isotopic labeling which reveals real-time deficits of microtubule-mediated neuronal transport.
Purchase a Triple Quadrupole Mass Spec-trometer (ESI-QQQ) to be used in Conjunction with a liquid chromatography system for targeted quantification of low molecular weight molecules and for the determination of isotopic labeling patterns of the quantified metabolites.
Many neurodegenerative diseases share altered microtubule function and neuronal axonal transport deficits which can be detected and quantified in the CSF of animals and humans using isotopic labeling of transported cargo proteins.
His research interests have been in areas relating to the shikimic acid pathway, including molecular modeling and NMR spectrometry of substrates and analogues, as well as structure and reactivity studies of shikimate pathway enzymes using isotopic labeling and mass spectrometry.