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One of two or more atoms or molecules having the same electron arrangement, for example, N2 and CO.
[iso- + G. stereos, solid]
References in periodicals archive ?
The term "isosteres" was defined for the first time (1919) by Langmuir in terms of isoelectronic or isosteric concept [6, 20] and thus emerged the concept of isosterism .
Erlenmeyer H (1932)-- Isosterism Concept Extension Erlenmeyer further extended the concept of isosterism [22] and reintroduced the term isosteres as atoms/elements, ions or molecules which exhibit similarity with respect to peripheral layers of electrons that is same number of electrons at the valance or peripheral level.
The pervasive applications of isosterism to biological system in search of therapeutically useful drugs raised the concept of bioisosterism.