isoquinoline


Also found in: Encyclopedia, Wikipedia.

i·so·quin·o·line

(ī'sō-kwin'ō-lēn),
1. Ring structure characteristic of the group of opium alkaloids represented by papaverine.
2. A class of alkaloids containing the isoquinoline (1) ring structure.
References in periodicals archive ?
Liang, Mucroniferanines A-G, Isoquinoline Alkaloids from Corydalis mucronifera, J.
Effects of organoselenium compound 2-(5-selenocyanato-pentyl)-benzo [de] isoquinoline 1, 3-dione on cisplatin induced nephrotoxicity and genotoxicity: An investigation of the influence of the compound on oxidative stress and antioxidant enzyme system.
Antiviral (Rna) Activity of Selected Amaryllidaceae Isoquinoline Constituents and Synthesis of Related Substances.
In this context, isoquinoline alkaloids, derived from one plant (Macleaya cordata) may become a relevant nutritional additive for beef cattle.
(15) These activities are due to the presence of the important alkaloid-containing phytoconstituents such as berlambine, dihydroberlambine, noroxyhydrastine, berberine(an isoquinoline alkaloid) and other constituents such asceryl-alcohol, saponin, hentriacontane, sitosterol glucoside, palmitic acid, and oleic acid, which are isolated from the stem and roots of the plants.
Drotaverine hydrochloride or isoquinoline 1,2,3,4-tetrahydro 6,7 diethoxy-1-(c-3,4-diethoxy phenyl methylene) hydrochloride is a highly potent spasmolytic agent, acting on the smooth muscle but is devoid of anticholinergic effects as it acts through inhibitory effect on phosphodiesterase enzyme, mainly PDEIV.
Quinolines, which consisted mostly of quinoline, alkyl quinoline, isoquinoline and benzoquinoline, constituted 25.33% of the concentrated product 1.
Kang et al., "Heme oxygenase-1 induction by (S)-enantiomer of YS-51 (YS-51S), a synthetic isoquinoline alkaloid, inhibits nitric oxide production and nuclear factor-kB translocation in ROS 17/2.8 cells activated with inflammatory stimulants," International Immunopharmacology, vol.
Berberine, found in Coptidis rhizome, is an isoquinoline alkaloid that has been used as a traditional Chinese medicine for thousands of years to treat gastrointestinal diseases, diarrhea, and bacterial infections [52], all of which are associated with the disruption of intestinal barrier function and TJ integrity.
Several studies have been conducted on its biological activities and more specifically on berberine, an isoquinoline alkaloid, considered as an active molecule with many properties such as hypoglycemic, antibacterial, antifungal, anti HCV, and anticancer activities [2-8].
The presence of isoquinoline alkaloids, the most important of which is protopine, is mainly associated with the biological activity of Fumaria spp.
Caption: Figure 11: The main structures of phenanthrene and isoquinoline [21, 22].