isonicotinic acid


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i·so·nic·o·tin·ic ac·id

(ī'sō-nik'ō-tin'ik as'id),
The substance of which the hydrazide is isoniazid.
References in periodicals archive ?
salicylic acid, nicotinamide (NIC), glutaric acid, malonic acid, benzoic acid, tartaric acid, oxalic acid, citric acid, urea, succinic acid, saccharine sodium, Pluronic 68 AR, magnesium stearate, crotonic acid, P-hydroxy benzoic acid, caffeine, 3,5 dihydroxy benzoic acid, piperazine citrate, cinnamic acid, adipic acid, hydroquinone, isonicotinic acid, acetamide, maleic acid, and ascorbic acid.
He, Studies on Lanthanide(III) Ternary Mixed-Ligand Complexes with N-(2-Propionic Acid)-Salicyloyl Hydrazone and Isonicotinic Acid: Synthesis, Characterization, and Antibacterial Activities, Synth.
"Acne-like lesions can occur in response to various compounds: corticosteroids, halogens, isonicotinic acid, diphenylhydantoin, and lithium carbonate.
The patient initiated prophylactic therapy with isonicotinic acid hydrazide (INH) for 6 months targeting recurrence of old pulmonary TB.
In the 1940s streptomycin and PAS (Para-Amino-salicylate Sodium) were introduced followed by thiocetazone and INH (Isonicotinic Acid Hydrazide) in 1950s.
INH, the hydrazide of isonicotinic acid, has been the mainstay of TB treatment and prevention since the 1950s.
Positive Oxyphenbutazone 16 07 Phenylbutazone 08 03 Acetyl salicylic acid 09 -- Analgin 13 01 Sulphadiazine 09 01 Sulphadimethoxine 07 -- Trimethoprim 11 -- Sulphamethoxazole 11 02 Dapsone 08 -- T etracycline 09 -- Oxytetracycline 06 -- Doxycycline 08 -- Paracetamol 02 -- Isonicotinic acid hydrazide 01 -- Thiacetazone 01 01 Procaine penicillin 08 --
Among these side effects hepatotoxicity is the one re- garded as serious and is the focus of the present study;2 3% cases of jaundice 7 8% of other side effects reported in hospitals and about 30% of sudden and severe liver failure are caused by drugs induced liver injury.4 Isoniazid is acetylated by the liver enzyme N- acetyltransferase 2 (NAT2) and then hydrolyzed resul- ting in formation of isonicotinic acid and acetylhydra- zine; the later compound is activated by cytochrome P-450.5 The metabolic oxidation of acetylhydrazine leads to reactive acetylating species diacetylhydrazine.
In this report, the synthesis of copper nanobuds by green chemical reduction using isonicotinic acid hydrazide is described.
It features "Isonicotinic Acid Ethyl Ester" (2010 - 2011) from internationally renowned artist Damien Hirst's Spot Paintings series.
The 3HP group was given once-weekly, directly observed treatment with rifapentine (brand name Priftin; 900 mg) plus isoniazid (brand name Nydrazid, also known as isonicotinic acid hydrazide or INH; 15-25 mg/kg) for 3 months.