Mice were anesthetized with isofluorane
and ventilated as described above.
Se encontraron datos variables en los costos de adquisicion de los halogenados gastados, que fueron menores para el isofluorane
, lo cual hacia tambien menos costosos los insumos anestesicos durante las cirugias; sin embargo, los costos en la sala de cirugia, en recuperacion y sala de ambulatorios y los costos totales no mostraron diferencias significativas.
Consequently, regional differences in CBF under isofluorane
anaesthesia are greatly reduced , and it is likely that this underlies the reduced regional variation in CBF observed in the current study.
Mutations in RYR1 gene, which causes abnormalities in the opening probability of the [Ca.sup.2+] channel, are also often associated to malignant hyperthermia (MH) susceptibility, an inherited pharmacogenetic subclinical myopathy, characterized by a life-threatening hypermetabolic response to commonly used halogenated/volatile anesthetics (i.e., halothane, isofluorane
) [8, 9].
Five hours later mice were anesthetized with 2.5% isofluorane
(Sigma Aldrich) in air and injected i.p.
All surviving animals were anesthetized with isofluorane
and euthanized by aortic exsanguination prior to necropsy.
Mice between p24 and p28 were deeply anesthetized with isofluorane
vapors in a chamber placed inside a chemical fume hood.
The pregnant rat was anaesthetized at ED17 with 4% isofluorane
in O2 and placed on a heating blanket at a sustained temperature of 37-38[degrees]C.
Effect of eletroacupuncture on minimum alveolar concentration of isofluorane
Live-trapped rodents were subsequently killed with isofluorane
. During necropsy, samples from lungs, spleens, and kidneys were collected and stored at -80[degrees]C until analysis.
MH is a potentially lethal disorder triggered in humans by administration of halogenated/volatile anesthetics (i.e., halothane and isofluorane
) and characterized by hyperthermia, rhabdomyolysis (i.e., the rupture of muscle fibers), and increased plasma/serum levels of [K.sup.+], [Ca.sup.2+], and creatine kinase (CK) [21,22].