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Antibacterial and antifungal related to ketoconazole and oxiconazole.
References in periodicals archive ?
Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy.
Antifungal agents are either polyenes (nystatin and am-photericin B) or azoles which are classified into: imidazoles (clotrimazole, econazole, fenticonazole, isoconazole, ketocon-azole, miconazole, sulconazole, tioconazole); and triazoles (fluconazole, itraconazole).
In gram-positive bacteria, accumulation of single oxygen species was observed after incubation with isoconazole nitrate (TravogenA/ TravocortA).
Isoconazole nitrate displays a broad spectrum of antimicrobial action against dermatophytes, yeasts, moulds and gram-positive bacteria.
Our data suggest that the bactericidal action of imidazoles such as isoconazole nitrate on gram-positive bacteria is based on the accumulation of reactive oxygen species, said Dr.
In Switzerland, three triazoles (terconazole, itraconazole, fluconazole) and eight imidazoles (clotrimazole, miconazole, econazole, ketoconazole, tioconazole, isoconazole, oxiconazole, and fenticonazole) are in use (Documed AG 2002).