isochromosome
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isochromosome
[i″so-kro´mo-sōm]an abnormal chromosome having a median centromere and two identical arms, formed by transverse, rather than normal longitudinal, splitting of a replicating chromosome.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
i·so·chro·mo·some
(ī'sō-krō'mō-sōm),A chromosomal aberration that arises as a result of transverse rather than longitudinal division of the centromere during meiosis; two daughter chromosomes are formed, each lacking one chromosome arm but with the other doubled.
Farlex Partner Medical Dictionary © Farlex 2012
i·so·chro·mo·some
(ī'sō-krō'mŏ-sōm)A chromosomal aberration that arises as a result of transverse rather than longitudinal division of the centromere during meiosis; two daughter chromosomes are formed, each lacking one chromosome arm but with the other doubled.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
isochromosome
An abnormal chromosome formed when, during the ANAPHASE of cell division, the CENTROMERE divides horizontally rather than longitudinally, thus producing a chromosome with two long arms and one with two short arms.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005