islet

(redirected from Islets)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Islets: IELTS, Langerhans islands

islet

 [i´let]
an island.
i's of Langerhans (pancreatic i's) irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
Walthard's i's microscopic inclusions of the ovarian germinal epithelium, which have been implicated in the development of Brenner tumors.

is·let

(ī'let),
A small island.

is·let

(ī'lĕt)
A small island.
References in classic literature ?
the people crossing over in the distance seemed unwilling even to look at the islet where the exiled effigy of the author of the Social Contract sat enthroned above the bowed head of Razumov in the sombre immobility of bronze.
Then he headed straight for Walrus Islet, a little low sheet of rocky island almost due northeast from Novastoshnah, all ledges and rock and gulls' nests, where the walrus herded by themselves.
Naturally the Chickies and the Gooverooskies and the Epatkas--the Burgomaster Gulls and the Kittiwakes and the Puffins, who are always looking for a chance to be rude, took up the cry, and--so Limmershin told me--for nearly five minutes you could not have heard a gun fired on Walrus Islet. All the population was yelling and screaming "Clam-eater!
Then he remembered in a flash what the Burgomaster gull had screamed to him when he was a little yearling at Walrus Islet, and he tumbled backward in the water, for he knew that he had found Sea Cow at last.
- US-based biotechnology company Semma Therapeutics, Inc has presented pre-clinical proof-of-concept based on data from its two lead programmes for type 1 diabetes testing stem cell-derived islets (SC-islets) in both non-human primates and pigs, the company said.
SERAXIS' leading technology includes GMP-grade, pure pancreatic islets that contain 60-90% of insulin-secreting beta cells.
The city government said Keelung Islet and adjacent islets are volcanic islets and blessed with exceptional natural landscapes and marine resources.
The alcoholism has a major effect on pancreatic islets cells and their insulin secretion.
"Because of the small numbers of islet transplantations performed and regulatory hurdles inherent in first-in-human trials, these promising therapies will take time to evaluate, but all represent potential major improvements toward more optimal use of islets for treatment of T1D."
Intrahepatic transplantation of pancreatic islets (PIs) represents an alternative treatment for unstable type 1 diabetic patients [1], but the procedure is associated with partial damage of liver tissue [2,3] and graft impairment due to blood-mediated inflammation, rejection, or hypoxia [4].
Although the mechanism of action for metformin is fairly well understood in hepatocytes, the direct effects metformin has on pancreatic islets and beta cells are less clear.
Due to their high oxygen dependence and lack of ability to scavenge free radicals, islets are particularly vulnerable to hypoxia [6].