amylin

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am·y·lin

(am'i-lin),
A 37-amino acid peptide that is cosecreted with insulin from the pancreatic β-cell. Many of its biologic activities mimic those of calcitonin gene-related peptide, which is not a β-cell peptide. In patients with Type 1 diabetes, amylin is essentially absent from the plasma. The plasma level of amylin rises after a meal or a glucose load.
[amyloid + -in]

amylin

(ăm′ə-lĭn)
n.
1. A peptide hormone that is secreted along with insulin by the beta cells of the pancreas and helps to regulate blood sugar levels by inhibiting glucagon secretion and by slowing the rate at which food leaves the stomach.
2. Archaic Any of various components of starch.

amylin

An older term for:
(1) (Pancreatic) islet amyloid polypeptide;
(2) Amylopectin.

am·y·lin

(am'i-lin)
The cellulose of starch; the insoluble envelope of starch grains.
References in periodicals archive ?
Jang et al., "Probing ion channel activity of human islet amyloid polypeptide (amylin)," Biochimica et Biophysica Acta--Biomembranes, vol.
channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels," Physical Chemistry Chemical Physics, vol.
Winter, "Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol," ChemBioChem, vol.
Raleigh, "Analysis of the inhibition and remodeling of islet amyloid polypeptide amyloid fibers by flavanols," Biochemistry, vol.
Betsholtz, "Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation," Proceedings of the National Academy of Sciences of the United States of America, vol.
Fraser, "Identification of minimal peptide sequences in the (820) domain of human islet amyloid polypeptide involved in fibrillogenesis," Journal of Structural Biology, vol.
Yang et al., "Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation," Diabetes, vol.
Raleigh, "Amyloid formation in heterogeneous environments: islet amyloid polypeptide glycosaminoglycan interactions," Journal of Molecular Biology, vol.
Serpell et al., "Identification of a novel human islet amyloid polypeptide sheet domain and factors influencing fibrillogenesis," Journal of Molecular Biology, vol.
Hamada, "Binding of islet amyloid polypeptide to supported lipid bilayers and amyloid aggregation at the membranes," Biochemistry, vol.
Leblanc, "Human islet amyloid polypeptide at the air-aqueous interface: a Langmuir monolayer approach," Journal of the Royal Society Interface, vol.
Lundquist, "Homologous islet amyloid polypeptide: effects on plasma levels of glucagon, insulin and glucose in the mouse," Diabetes Research and Clinical Practice, vol.