amylin

(redirected from Islet amyloid polypeptide)
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am·y·lin

(am'i-lin),
A 37-amino acid peptide that is cosecreted with insulin from the pancreatic β-cell. Many of its biologic activities mimic those of calcitonin gene-related peptide, which is not a β-cell peptide. In patients with Type 1 diabetes, amylin is essentially absent from the plasma. The plasma level of amylin rises after a meal or a glucose load.
[amyloid + -in]

amylin

(ăm′ə-lĭn)
n.
1. A peptide hormone that is secreted along with insulin by the beta cells of the pancreas and helps to regulate blood sugar levels by inhibiting glucagon secretion and by slowing the rate at which food leaves the stomach.
2. Archaic Any of various components of starch.

amylin

An older term for:
(1) (Pancreatic) islet amyloid polypeptide;
(2) Amylopectin.

am·y·lin

(am'i-lin)
The cellulose of starch; the insoluble envelope of starch grains.

amylin

see amyloid.
References in periodicals archive ?
25] Several amyloid proteins that are derived from various hormones ([pro]calcitonin, islet amyloid polypeptide, atrial natriuretic factor, prolactin, insulin, and lactoferrin) are in general associated with endocrine gland pathologic conditions.
Editor's Note: As potential mechanisms, the authors note that zinc is needed for insulin's action, for carbohydrate metabolism, to moderate inflammatory cytokine levels that can destroy beta cells, for preventing human islet amyloid polypeptides from aggregating to form amyloid fibers that have a toxic effect on beta cells, to reduce oxidative stress and for other protective functions.