In our recently paper on Non-Arteritic Ischemic Optic Neuropathy
, over 73% of reported eyes treated with our methodology improved (p< .
SUMMARY--The aim of this study was to assess damage to retinal ganglion cells (RGC) and morphology of the optic nerve head (ONH) in patients with primary open angle glaucoma (POAG) and non-arteritic anterior ischemic optic neuropathy
In a study seeking to answer the question of whether all retinal nerve fiber layer (RNFL) defects are glaucomatous, Gur Gungor and Akman reassessed patients initially diagnosed with glaucoma based on RNFL damage detected on OCT and found that the ocular findings of some of those patients were actually due to different conditions such as ischemic optic neuropathy
, optic neuritis associated with multiple sclerosis, optic disc drusen, and pseudotumor cerebri.
Ischemic optic neuropathy
(ION) refers to infarction of any portion of the optic nerve from the chiasm to optic nerve head.
sup], EB has been used to establish animal models of posterior ischemic optic neuropathy
, neuropathic pain, and distal occlusion of the arteria cerebri media.
A total of 82 patients were involved in the study, some with glaucoma, others with anterior ischemic optic neuropathy
and a smaller proportion with more than one cause of optic nerve atrophy.
Various ophthalmological diseases, such as keratoconjunctivitis sicca, macular edema, and ischemic optic neuropathy
have also been reported in the course of HCV infection (13).
Diagnoses included ischemic optic neuropathy
, uveitis, and retinal detachment.
In the ocular system many lines of evidence indicate that hHcy is a risk factor in a variety of disease including retinal atherosclerosis, cataract, glaucoma, exudative age related macular degeneration, macular and optic atrophy due to retinal vascular occlusions and non arteritic ischemic optic neuropathy
Sene et al3 reported occurrence of Vogt-Koyanagi-Harada (VKH) like disease central retinal vein occlusion central retinal artery occlusion and bilateral ischemic optic neuropathy
in patients receiving INF.
Diseases covered include cerebrovascular disorders, traumatic brain injury, spinal cord injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, epilepsy and ischemic optic neuropathy
as well as retinal degeneration.
QPI-1007 is entering global Phase III studies for the treatment of non-arteritic anterior ischemic optic neuropathy
(NAION) and a pilot Phase II study for the treatment of acute angle closure glaucoma.