ischemic cascade

(redirected from Ischaemic cascade)

ischemic cascade

Vascular disease A series of events lasting for hrs to several days after an initial ischemic event that results in extensive necrosis and tissue damage beyond the tissue zone first affected by the initial lack of blood flow
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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Activation of proteins such as the metalloproteinases (MMPs) by the ischaemic cascade is likely one of the elements in BBB leakage [1], resulting in haemorrhagic transformation and increased oedema.