iron-sulfur protein

(redirected from Iron-sulfur center)

i·ron-sul·fur pro·tein

protein containing one or more iron atoms that are linked to sulfur bridges and/or sulfur of cysteinyl residues; for example, some proteins in the electron transport pathway.
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References in periodicals archive ?
Like the entamoebic Fe-hydrogenase 1, the predicted giardial Fe-hydrogenase lacked an N-terminal organelle-targeting sequence and had two ferredoxin-like iron-sulfur centers and a hydrogenase iron-sulfur center like those present in the short Fe-hydrogenases of T.
The structures of a short Fe-hydrogenase of Desulfovibrio desulfuricans and a long Fe-hydrogenase of Clostridium pasteurianum have been solved, and each revealed two ferredoxin-like [4Fe-4S] iron-sulfur centers and a hydrogenase active-site composed of a [4Fe-4S] center bridged to a [2Fe] clus ter (Peters et al., 1998; Nicolet et al., 1999).
This was likely caused b y exposure to oxygen during the purification procedure that probably inactivated the Fe-hydrogenase 1 iron-sulfur centers (Cammark, 1992; Payne et al., 1993; Homer et at., 2000).
Intracellular iron is either tightly bound within iron-containing proteins (e.g., those factors with iron-sulfur centers) or more transiently associated with low-molecular-weight (LMW) ligands (Huang 2003).