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mecamylamineA nonselective and noncompetitive ganglion-blocker once used to treat severe malignant hypertension. Mecamylamine binds ± 1/2 of nicotinic acetylcholine receptors; it may be effective in smoking cessation and can be used with nicotine replacement therapy (e.g., gum or patches). It may reduce tics and rage reactions in Tourette syndrome.
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