Anidulafungin versus fluconazole for invasive candidiasis
. N Engl J Med.
Epidemiology of invasive candidiasis
. Curr Opin Crit Care.
We report on 23 cases of invasive candidiasis
caused by C.
Contribution of serum biomarkers to the diagnosis of invasive candidiasis
. Expert Rev Mol Diagn 2008;8:315-25.
Drug Indications Dose Amphotericin B Neonates with disseminated 1 mg/kg/day candidiasis intravenously including CNS disease candidiasis, invasive candidiasis
, mucosal aspergillosis cryptococcal meningitis coccidioidomycosis histoplasmosis blastomycosis mucormycosis sporotrichosis Liposomal Same as above with 3-5 mg/kg/day amphotericin B exceptions noted above intravenously Drug Special comments Amphotericin B Conventional preferred for 1.
There is considerable regional variability, and therefore, local epidemiological knowledge is critical in the effective management of invasive candidiasis
. Only a few studies from India have reported candidemia rates of 6-18%, [2,3] and an increase in isolation of non-albicans candida (NAC) species from blood samples [4,5] has been reported.
Currently, the most commonly isolated agent in cases of invasive candidiasis
is Candida albicans, but the frequency of non-albicans species is gradually increasing.
Proceeds of the financing will be used to advance the development of Amplyxs lead candidate APX001 into Phase II clinical trials for the treatment of invasive candidiasis
, aspergillosis, and rare molds, including Fusarium, Scedosporium, and fungi from the Mucorales order.
as a cause of sepsis in the critically ill patient.
Epidemiology of candidemia and Invasive candidiasis
In the last years, the incidence of healthcare-associated fungal infections has been rising, mainly of invasive candidiasis
Common invasive fungal diseases: an overview of invasive candidiasis
, aspergillosis, cryptococcosis, and Pneumocystis pneumonia.