Chemotherapy plus local treatment in the management of intraocular retinoblastoma
. Arch Ophthalmol.
: the case for a new group classification.
Linn, "Intraocular retinoblastoma
: the case for a new group classification," Ophthalmology Clinic of North America, vol.
Therefore, IVC is recommended as the first line treatment for germ-line mutation retinoblastomas (bilateral, familial), particularly to protect patients from pineoblastoma and second cancers and, in addition, to achieve control of the intraocular retinoblastoma
and to prevent metastasis .
A phase I/II study of direct intra-arterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma
- initial results.
The International Intraocular Retinoblastoma
Classification System (IIRC) separates retinoblastomas into groups (A-E) based on prognosis, which is related to the extent of intraocular disease at diagnosis (Supplemental Table 1 will be available online at http://dx.doi.org/10.1155/2013/975908).
Treatment of intraocular retinoblastoma
with vincristine and carboplatin.
A phase I/II study of subconjunctival carboplatin for intraocular retinoblastoma
. Ophthalmology.1999; 106: 1947-50.
Second malignant neoplasms following chemoreduction with carboplatin, etoposide, and vincristine in 245 patients with intraocular retinoblastoma
. Pediatr Blood Cancer.
There are few studies that have evaluated HRFs in eyes enucleated for advanced intraocular retinoblastoma
from developing countries, and most of them have reported higher incidences compared with studies reported in the Western literature.
Pilot studies of chemotherapy for intraocular retinoblastoma
have been reported from several groups using different combinations, dosages, schedules and duration of carboplatin, etoposide or teniposide, with or without vincristine, and with or without cyclosporine to counteract multidrug resistance.
Results of combined chemotherapy and radiotherapy for advanced intraocular retinoblastoma
. Arch Ophthalmol.