neuronal intestinal dysplasia

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neu·ro·nal hy·per·pla·si·a

increased numbers of ganglion cells with myenteric plexus hyperplasia and increased acetylcholinesterase activity in nerves of the mucosa and submucosa. Clinically, neuronal hyperplasia mimics Hirschsprung disease. Similar findings are seen in patients with multiple endocrine neoplasia syndrome, type IIB, and in neurofibromatosis.
Farlex Partner Medical Dictionary © Farlex 2012

neuronal intestinal dysplasia

Abbreviation: NID
A disorder of bowel motility in which the innervation of the intestines is ectopic (the ganglions that provide nervous control of intestinal musculature being misplaced).
See also: dysplasia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
In one of these 2 biopsies, ganglion cells were identified within the perineurial ring (Figure 4), a feature that has been reported in intestinal neuronal dysplasia.[16]
One of these biopsies demonstrated intraperineurial ganglion cells, a feature that had been reported as suggestive of intestinal neuronal dysplasia.[18,19] The finding of increased numbers of fibers of all sizes and of enlarged fibers is unexplained, but raises the possibility of neuronal dysplasia in ganglionic areas of bowel.
Rectal mucosal biopsy compared with laparoscopic seromuscular biopsy in the diagnosis of intestinal neuronal dysplasia in children with slow-transit constipation.
Intestinal neuronal dysplasia. Eur J Gastroenterol Hepatol.
Laparoscopic extensive colectomy with transanal Soave pull-through for intestinal neuronal dysplasia in 17 children.
(8) The open colectomy has been performed for intestinal neuronal dysplasia type B due to its feasibility and low morbidity rate.
Intestinal neuronal dysplasia: does it exist or has it been invented?
[15.] R Gath, A Goessling, et al, Analysis of the RET, GDNF, EDN3, and EDNRB genes in patients with intestinal neuronal dysplasia and Hirschsprung disease, Gut: 2001, 48:671-675.
Clinical aspects of intestinal neuronal dysplasia. J Pediatr Surg.
Bruder et al., "Updated results on intestinal neuronal dysplasia (IND B)," European Journal of Pediatric Surgery, vol.
Malformations in the reserved segment are mainly type B intestinal neuronal dysplasia and hypoganglionosis.[sup][70],[71]
Three patients had megacystis microcolon intestinal hypoperistalsis (MMIH), 2 had intestinal neuronal dysplasia (IND), 2 had Waardenburg syndrome (WS), and 1 had enteric anendocrinosis (EA), while the etiological cause could not be found for 5 patients.

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