We reflect upon the significant problems that prevent universal acceptance of IND B as cause of intestinal dysmotility
, and we illustrate how some contemporary publications perpetuate unjustified misconceptions about IND B based on evidence that lacks sufficient scientific rigor.
, mechanical obstruction, and extensive small bowel mucosal disease are rare causes of type III, chronic IF (1,2).
We believe applying this technique to mouse models of intestinal pathology will shed light on the involvement of both contracting and relaxing agents that result in intestinal dysmotility
. Our future studies will be directed towards assessing pharmacological tools to reduce the distance between consecutive contractile events in ob/ob mouse intestines (i.e., returning towards lean levels).
These findings indicate that impairment of the PKC-mediated signalling pathway in colonic SMCs played a role in the pathogenesis of intestinal dysmotility
in experimental AP.
can be associated with nausea and vomiting, bloating, or even visible distension [48, 49].
It has traditionally been thought to result from two abnormalities: visceral hypersensitivity and intestinal dysmotility
. However, recent intensive studies have revealed that low-grade inflammation of the intestines , as well as alterations of gut barrier function, epithelial permeability, mucosal immunity, and gut-brain axis [5-8], is also involved.
Its etiology may be idiopathic or secondary to various predisposing factors like suture lines, adhesions, submucosal bowel edema, intestinal dysmotility
, long intestinal tubes and chronic dilatation of bowel.
[TLR2.sup.-/-] mice demonstrated disrupted ENS architecture as well as intestinal dysmotility
that could be corrected by the addition of glial cell line-derived neurotrophic factor (GDNF).
She was diagnosed with intestinal dysmotility
syndrome or pseudo-obstruction.
Common medical conditions that predispose a child to feeding problems include structural abnormalities, like transesophageal fistula, esophageal atresia, congenital diaphragmatic hernia, or strictures; GI motility problems, including intestinal dysmotility
and gastroesophageal reflux; other GI conditions, like food allergy or celiac disease; general medical illnesses, like cancer or cancer therapy, burns, or trauma; and chronic conditions of the lung, heart, or kidneys.
, common in cirrhosis, causes an overgrowth of urease-positive bacteria and increased nitrogen absorption.