intermediate density lipoprotein


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in·ter·me·di·ate den·si·ty lip·o·pro·tein (IDL),

class of lipoproteins formed in degradation of very low density lipoproteins; about half are cleared quickly from the plasma into the liver by receptor-mediated endocytosis; the other half are degraded into low density lipoproteins.

intermediate density lipoprotein

Physiology A plasma lipoprotein with a density of 1.006-1.019 g/dl, formed by lipoprotein lipase hydrolysis of VLDL partially depleted of TGs Composition 15% protein, predominantly apoB and apoE, 25% phospholipid, 30% cholesterol, 30% TGs Role Transports cholesterol from intestine to liver; once in the liver, is delipidated by hepatic lipoprotein lipase to form a low-density protein

in·ter·me·di·ate den·si·ty lip·o·pro·tein

(intĕr-mēdē-ăt densi-tē lipō-prōtēn)
Class of lipoproteins formed in degradation of very low density lipoproteins.
References in periodicals archive ?
It was later discovered that it is the major protein component of chylomicrons, chylomicron remnants, VLDL, intermediate density lipoprotein, LDL, and lipoprotein(a); it is absent from HDL.
VLDL and intermediate density lipoprotein were removed by aspiration after the first ultracentrifugation run ([267 000g.sub.av], 2 h 40 min, 15[degrees]C).
VLDL, intermediate density lipoprotein (IDL), and LDL were prepared by sequential ultracentrifugation of the chylomicron infranatant at densities of 1.006, 1.019, and 1.063 kg/L, respectively, for 18 h each.
[6] Nonstandard abbreviations: nonHDLc, nonhigh density lipoprotein cholesterol; apo B, apolipoprotein B; LDLp, LDL particle concentration; CHD, coronary heart disease; LDLc, LDL cholesterol concentration; IDL, intermediate density lipoproteins; CVD, cardiovascular disease; WHS, Women's Health Study; TC,total cholesterol; MI, myocardial infarction; CABG, coronary artery bypass graft; HR, hazard ratio; MetS, metabolic syndrome; BMI, body mass index; hsCRP, high-sensitivity C-reactive protein; ASCVD, arteriosclerotic cardiovascular disease.

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