IL19

(redirected from Interleukin-19)

IL19

A gene on chromosome 1q32.2 that encodes interleukin-19, a cytokine which plays a role in inflammation by upregulating IL-6 and TNF-alpha and inducing apoptosis.
References in periodicals archive ?
Fielding, "Interleukin-19: A new target to aim for?" Rheumatology, vol.
Funding et al., "The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis," British Journal of Dermatology, vol.
Chan, "Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites," The Journal of Immunology, vol.
Gallagher, "Interleukin-19: Multiple roles in immune regulation and disease," Cytokine & Growth Factor Reviews, vol.
Chen et al., "Interleukin-19 upregulates keratinocyte growth factor and is associated with psoriasis," British Journal of Dermatology, vol.
Hu et al., "The association between interleukin-19 concentration and diabetic nephropathy," BMC Nephrol, vol.
Hsu et al., "The distribution of interleukin-19 in healthy and neoplastic tissue," Cytokine, vol.
Kozlov et al., "Crystal structure of interleukin-19 defines a new subfamily of helical cytokines," Journal of Biological Chemistry, vol.
Eskdale et al., "Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)," Genes and Immunity, vol.
Chang, "Induction of interleukin-19 and interleukin-22 after cardiac surgery with cardiopulmonary bypass," Annals of Thoracic Surgery, vol.
Kozlov et al., "Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20," Biochemistry, vol.
Punch biopsies in 18 patients with psoriasis revealed that expression of interleukin-20 (IL-20) and interleukin-19 (IL-19) was elevated by a factor of 22 and 65, respectively, in lesional skin, compared with nonlesional skin.