IL25

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IL25

A gene on chromosome 14q11.2 that encodes interluekin-25, a proinflammatory cytokine that induces activation of NF-kappa-B and stimulates proinflammatory IL-8 production. IL25 favours Th2-type immune responses.
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References in periodicals archive ?
Wang et al., "Interleukin 25 promotes the initiation of proallergic type 2 responses," The Journal of Experimental Medicine, vol.
The new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune systems response to inflammation, for the express purpose of killing nearby breast cancer cells.
Corry, both of whom are associate professors of Medicine-Pulmonary at BCM as well as senior authors of the study report, point out that that MMP7 particularly activates interleukin 25, a key mediator of the allergic response in the lung.