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[T.sub.FH] cells primarily exert their function through the secretion of interleukin 21
Interleukin 21 (IL-21) has a pleiotropic effect on inflammation regulation.
Expression of interleukin 21 and interleukin 21 receptor in muscle tissues of patients with dermatomyositis and polymyositis
The signaling activation of Th17 induces the production of interleukin 17 (IL-17), interleukin 21 (IL-21) and interleukin 22 (IL-22).
 described a new subset of follicular helper T (Tfh) cells and interleukin 21 (IL-21), which regulate the development of antigen-specific B-cell immunity, present in human autoimmune thyroid diseases (AITD) (as Graves' disease (GD) and HT).
Higher frequency of peripheral blood interleukin 21
positive follicular helper Tcells in patients with ankylosing spondylitis.
Abbreviations IL-21: Interleukin 21
IL-21R: Interleukin 21
receptor TNF-[alpha]: Tumour Necrosis Factor alpha IL-1[beta]: Interleukin 1 beta MRI: Magnetic resonance imaging.
30 September 2010 - US-based biopharmaceutical company ZymoGenetics Inc (NASDAQ: ZGEN) yesterday announced positive survival data from a Phase IIa clinical trial in metastatic melanoma with recombinant Interleukin 21
(IL-21) as a single agent.
IRF-4-binding protein inhibits interleukin 17 and interleukin 21
production by controlling the activity of IRF-4 transcription factor.