XCUR17 is an SNA drug targeted to mRNA encoding interleukin 17
receptor alpha, or IL-17RA.
Serum interleukin 17
and interleukin 18 levels in familial Mediterranean fever.
Suraci et al., "Enhanced expression of indoleamine 2, 3-dioxygenase in Helicobacter pylori-infected human gastric mucosa modulates Th1/Th2 pathway and interleukin 17
production," Helicobacter, vol.
Indicator Reagent set Manufacturer Measurement range Interleukin 17
Human IL-17A eBioscience, 0.5-100.0 (IL-17A) Platinum ELISA USA pg/ml Transforming TGF-[[beta].sub.1]- eBioscience, 31.250-2000 growth mU/ml USA pg/ml factor-[beta] (TGF-[[beta].
As such, it is possible that interleukin 17
blockade may contribute to a shift to the T-helper 1 cell-mediated development of GA.
Fountain et al., "Pathological role of interleukin 17
in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis," The Journal of Experimental Medicine, vol.
(IL-17) is a common denominator of various inflammatory diseases and has a crucial role in the pathogenesis of PsA and psoriasis.
contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis.
inhibits myogenic and promotes osteogenic differentiation of C2C12 myoblasts by activating ERK1,2.
* Markers of inflammation in the blood (interleukin 17
and Activin A) were significantly reduced in the MPC-treated group compared with saline-treated controls over the two-week study period
So, "Effect of interleukin 17
on proteoglycan degradation in murine knee joints," Annals of the Rheumatic Diseases, vol.
We evaluated the following pro-inflammatory cytokines: interleukin 1 b (IL-1[beta]), interleukin 2 (IL-2), IL 2 receptor (IL-2R), interleukin 5 (IL-5), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 12 (IL-12), interleukin 15 (IL-15), interleukin 17
(IL-17), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), eotaxin, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon [alpha] (IFN-[alpha]), interferon [gamma] (IFN-[gamma]), monokine induced by IFN-[gamma] (MIG), inducible protein 10 (IP-10), monocyte chemotactic protein 1 (MCP-1), macrophage inflammatory protein-1[alpha] (MIP-1-[alpha]), macrophage inflammatory protein-1[beta] (MIP-1-[beta]), and tumor necrosis factor [alpha] (TNF-[alpha]).