interleukin-1

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Related to Interleukin 1: Interleukin 2

in·ter·leu·kin-·1

(in'tĕr-lū'kin),
A cytokine, derived primarily from mononuclear phagocytes, that enhances the proliferation of T-helper cells and the growth and differentiation of B cells. Il-1 induces the release of Il-2. When secreted in larger quantities, IL-1 is a mediator of inflammation, entering the bloodstream and causing fever, inducing synthesis of acute phase proteins, and initiating metabolic wasting. There are two distinct forms of IL-1:, α and β, both of which perform the same functions but represent different proteins.

interleukin-1

(ĭn′tər-lo͞o′kĭn-wŭn′)
n.
Any of a family of cytokines that are released by macrophages and other cells and stimulate the inflammatory response.

in·ter·leu·kin-1

(in'tĕr-lū'kin)
A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells.

interleukin-1

A powerful polypeptide hormone produced by MACROPHAGES and fibroblasts that acts on LYMPHOCYTES to increase their ability to respond to ANTIGENS. Interleukin-1 is also responsible for resetting the temperature regulating mechanism at a higher level and thus causing fever, for the induction of the release of ACUTE PHASE PROTEINS, and for promoting the absorption of bone by OSTEOCLASTS.

in·ter·leu·kin-1

(in'tĕr-lū'kin)
A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells.
References in periodicals archive ?
Vaes, "Modulation by interleukin 1 and tumor necrosis factor a of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes," Biochimica et Biophysica Acta--Molecular Cell Research, vol.
Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease.