remains the first line treatment for patients with hepatitis D virus and more than one year therapy may be necessary.
They were divided in to two groups, one who used interferon
and the other who did not.
Studies that have directly compared interferon
alpha-2a and interferon
alpha-2b have been "limited in sample size or scope" and have arrived at disparate conclusions, the investigators said.
Sibley quickly proposed that interferon
could be used to tamp them down.
Prevention of lethal respiratory vaccinia infections in mice with interferon
(IFN)-a and IFN-g.
With all interferons
, animals given large doses have had abortions, but this does not appear to occur with doses used clinically.
Plantation, FL; 954-233-8746) announced it has been granted United States Patent 6,350,589 from the United States Patent and Trademark Office for a process relating to the manufacture of human natural alpha interferon
from human white blood cells.
Headquartered in Cambridge, MA, the company's revenues are generated from international sales of AVONEX (Interferon
beta-1a) for treatment of relapsing forms of multiple sclerosis, and from the worldwide sales by licensees of a number of products, including alpha interferon
and hepatitis B vaccines and diagnostic products.
Research thus far has concentrated on the drugs' enhancement of interferon
and natural killer cell activity, which Carter calls the "fighting couple" of the immune system.
Activation of interferon
regulatory factor 3 is inhibited by the influenza A virus NS1 protein.
This seeming dead end led him to study the then newly identified interferon
molecules, which are produced by immune-system cells.