IRF1

(redirected from Interferon Regulatory Factor 1)
Also found in: Acronyms.

IRF1

A gene on chromosome 5q31.1 that encodes interferon regulatory factor 1, a protein of the interferon regulatory transcription factor (IRF) family, which activates interferon (IFN) alpha and beta transcription, and acts as a transcription activator of genes induced by IFNs alpha, beta and gamma. IRF1 also plays a role in regulating apoptosis and tumour-suppression.
Mentioned in ?
References in periodicals archive ?
Itoh, "Cooperative contributions of interferon regulatory factor 1 (IRF1) and IRF8 to interferon-[gamma]-mediated cytotoxic effects on oligodendroglial progenitor cells," Journal of Neuroinflammation, vol.

Full browser ?