intercellular adhesion molecule


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intercellular adhesion molecule

,

ICAM

Any of a group of immunoglobulin-like proteins on the surface of cells that help them bind to each other or to the extracellular matrix that surrounds them. These proteins also participate in cell-to-cell signaling, cytokine production, and cellular reproduction.
References in periodicals archive ?
Intercellular adhesion molecule 1 (ICAM-1) gene variant is associated with coronary artery calcification independent of soluble ICAM-1 levels.
Intercellular adhesion molecules (ICAM-1) and Vascular cell adhesion molecules (VCAM-1) belong to Ig superfamily and both are involved in immune reaction [11].
Grzelewska-Rzymowska, "Intercellular adhesion molecule 1 and tumor necrosis factor a in asthma and persistent allergic rhinitis: relationship with disease severity," Annals of Allergy, Asthma and Immunology, vol.
Model 2 adds C-reactive protein, homocysteine, fibrinogen, soluble intercellular adhesion molecule 1, and hemoglobin [A.sub.1c] to model 1.
For the present study, they evaluated self-reported migraine and aura status with levels of total cholesterol, LDL cholesterol, HDL cholesterol, non-HDL cholesterol, apolipoprotein A-I, apolipoprotein B-100, lipoprotein, CRP, fibrinogen, soluble intercellular adhesion molecule 1, homocysteine, and creatinine.
Antibodies for whole-cell ELISAs using cell-surface-expressed method for E-selectin or intercellular adhesion molecule 1 (ICAM-1) were obtained from R&D Systems (Minneapolis, Minnesota).
aLb2(CD102) is also known as intercellular adhesion molecule 2 (ICAM-2).
AECAs were reported to induce the secretion of interleukin (IL)-1[beta], IL-6, IL-8, and monocyte chemotactic protein-1, (MCP-1), and the expression of adhesion molecules such as E-selectin, intercellular adhesion molecule 1 (ICAM-1), and vascular cell adhesion molecule 1 (VCAM-1) [8, 24, 31], which cause leukocyte recruitment and adhesion.
In that study, we evaluated a panel of 12 vascular biomarkers that included lipid fractions and apolipoproteins, homocysteine, lipoprotein(a), and 4 inflammatory biomarkers [hsCRP, soluble intercellular adhesion molecule 1 (sICAM-1), interleukin (IL)-6, and serum amyloid A (SAA)] as potential determinants of future vascular events among otherwise healthy American women.
Low 25-hydroxyvitamin D levels were significantly correlated with variables of inflammation (C-reactive protein and interleukin 6 levels), oxidative burden (serum phospholipid and glutathione levels), and cell adhesion (vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 levels).
Homocysteine, fibrinogen, soluble intercellular adhesion molecule 1, and creatinine measures did not add to the accuracy of risk prediction, nor did body mass index or exercise frequency, Dr.