Around the adenomere it is possible to distinguish stellate myoepithelial cells, as well as around the
intercalated ducts (Leal et al., 2003; Amano et al., 2012).
Oncocytomas originate mainly from the
intercalated duct cells consequently most of the oncocytomas occur in the parotid gland abundant in
intercalated ducts.
It arises specifically from the
intercalated ducts, and electron microscopy shows that it arises from cells that can differentiate into epithelial and myoepithelial cells.
Histologically, the tumour is biphasic with clear myoepithelial cells surrounding epithelial-lined ducts resembling
intercalated ducts [3].
Sometimes ducts open directly into cysts and some acinar units communicate with the cyst suggesting its origin from
intercalated ducts. There is flocculent, eosinophilic material and a few scattered macrophages found in most of the cystic lumina.
Myoepithelial cells are specialized basal epithelial cells that are found in the secretory endpieces and
intercalated ducts of the normal exocrine glands, such as the salivary glands, respiratory tract glands, lacrimal glands, mammary glands, prostate glands, and sweat glands.
(13) Recently, Ohtomo et al (14) found SOX10 was expressed in both luminal and abluminal cells of
intercalated ducts of normal human major salivary glands.
Intercalated ducts were present close to developing islet tissue in the twenty specimens of groups A and B and not present in group C.
Results: The mean number of
intercalated ducts in the right gland "a" and "b" parts, and in the left gland "a" and "b" parts was 1.45 +- 0.14, 1.39 +- .009, 1.31 +- 0.11 and 1.18 +- 0.10 respectively.
The luminal diameter of acini was larger and had more of secretory granules than the
intercalated ducts. The rough endoplasmic reticulum elongated into spiral form in the infranuclear cytoplasm of the epithelial cells.
In head and neck pathology, discovered on gastrointestinal stromal tumor protein 1 (DOG1) expression was seen in normal serous acini, mucous acini, and distal
intercalated ducts. All acinic cell carcinomas were positive for DOG1, with predominantly apical/luminal membranous staining.
Plenty of
intercalated ducts, striated and excretory ducts are seen scattered.
