intercalated disc

(redirected from Intercalated disks)
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in·ter·ca·la·ted disc

a specialized intercellular attachment of cardiac muscle cells comprising gap junctions, fascia adherens, and occasionally desmosomes.

in·ter·ca·la·ted disc

(in-tĕr'kă-lā-tĕd disk)
A histologic feature of cardiac muscle, occurring at the junction of two myocardial cells; site of intercellular passage of ions and electrical impulses.
References in periodicals archive ?
Arrhythmias are probably the result of gap junctions remodeling in intercalated disks and sodium flux downregulation, due to interrelationships between desmosomes, gap junctions, and voltage-gated sodium channels [41].
Trichromic staining may evidentiate discrete areas of fibrosis and the remodeling of intercellular intercalated disks is evident in electron microscopy [1].
It is also plausible that the two mentioned mechanisms are intricated, as more as ARVC is currently considered a disease of the intercalated disk, as a carrefour of desmosomal and non-desmosomal close interactions [31, 41].