intercalated disc

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in·ter·ca·la·ted disc

a specialized intercellular attachment of cardiac muscle cells comprising gap junctions, fascia adherens, and occasionally desmosomes.
Farlex Partner Medical Dictionary © Farlex 2012

in·ter·ca·la·ted disc

(in-tĕr'kă-lā-tĕd disk)
A histologic feature of cardiac muscle, occurring at the junction of two myocardial cells; site of intercellular passage of ions and electrical impulses.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Intercalated discs, numerous in the rat atrium of the MI treated group showed marked irregularity of its fascia adherence and desmosomes are observed.
Intercalated discs and arrhythmogenic cardiomyopathy.
Morphological features of Sham-operated, myocardial infarction (MI), and MI+ghrelin-treated Rats No Aspects Sham-operated control Rats Atrionatriunetic factor Aggregations of small electron dense granules 1 (ANF) granules occumulated in the central parts of cell close to nucleus and between plasma membrane and peripheral myofibrils Intercalated discs Longitudinal segments running parallel to the 2 myofilaments * Fascia adherence Intact * Desmosomes Intact * gap junctions Intact Myocardial cells Noimal architecture 3 * Myofibrils Preserved sarcomeres * Z and H bands Clear bands (Z and H).
Ghrelin Improves the Fine Structure of Atrial Natriuretic Factor (ANF) Granules and Intercalated Disc Junctions in Experimentally-Induced Myocardial Infarction in Rats
2 C and D), intact intercalated disc with clear identification of fully formed fascia adherence and desmosomes (Fig.
Normal distribution of atrionatriuretic factor (ANF) granules, an intact intercalated disc with clear identification of fully formed fascia adherence and desmosomes with a reconstruction of gap junction (nexus) were also noticed.
The reason for this is, that it is difficult to identify the intercalated discs and, also at times, to identify the lateral borders of the myocytes.
Objective: mXin[alpha], a downstream target gene of Nkx2.5 transcription factor, was shown to encode a proline-rich and Xin repeats-containing protein which localizes to the intercalated disc of adult hearts.
Targeted deletion of mXin[alpha] gene, encoding an intercalated disc protein, leads to cardiac hypertrophy (Abstract).
2) are tightly packed with obliquely striated myofibers and contact each other by small desmosomes and intercalated discs (Fig.
Microscope Digital Both n= 30 (32.3%) n= 34 (36.5%) n= 29 (31.2%) Cardiac muscle 22 (73.3%) 26 (76.5%) 27 (76.5%) Intercalated discs 11 (36.7%) 7 (20.6%) 6 (20.7%) Endomysium 17 (56.7%) 19 (58.8%) 26 (89.7%) Muscle fibers 17 (56.7%) 20 (58.8%) 24 (82.8%) Smooth muscle 22 (73.3%) 27 (79.4%) 28 (96.6%) Muscle fibers 19 (63.3%) 24 (70.6%) 25 (86.2%) Nucleus 17 (56.7%) 20 (58.8%) 23 (79.3%) Endomysium 12 (40.0%) 14 (41.2%) 23 (79.3%) Skeletal Muscle 27 (90.0%) 26 (79.5%) 22 (75.9%) Muscle fibers 25 (83.3%) 23 (67.7%) 20 (68.9%) Endomysium 28 (93.3%) 22 (64.7%) 24 (82.8%) Perimysium 29 (96.7%) 21 (61.8%) 23 (79.3%)