interactome

(redirected from Interactomes)

interactome

(int″ĕ-rak′tōm″) [ interact + -ome]
All of the potential chemical reactions that can take place within the macromolecules of a cell.
References in periodicals archive ?
To further understand the downstream pathways through which Notch3 and Notch4 mediate ozone-induced lung inflammation, we used genome-wide transcriptome analysis to identify candidate gene transcripts and interactomes.
Characterization of protein interactomes and their effects on gene expression will identify common cellular denominators of MPT families, whose functional contribution will be assessed through pooled shRNA screens in clinically relevant model systems.
Systems biology approaches and tools for analysis of interactomes and multi-target drugs.
Integrating Interactomes, 295 SCIENCE 284, 285 (2002).
Diagrams of interactomes look a bit like webs made by deranged spiders.
Comparing species' interactomes provides another way for scientists to explore the evolution of complex animals beyond just comparing the "parts list" of genes encoded in the genome.
While the interactome encompasses more of an organism's complexity than the genome alone, Stumpf says that comparing interactomes captures only part of the total difference in complexity between species.
That network of interactions, or "interactome," is about 10 times larger than that of the fruit fly and three times the size of the roundworm's interactome.
At least when we score on the basis of interactome size, the humans come out on top" in comparison with fruit flies and roundworms, Bonhoeffer says.
Different levels of evolution are considered, from internal modules in genes and proteins to interactomes and biological networks.
Mapping the most significantly changed miRNAs to their predicted mRNA targets and their network interactomes within the cell revealed the association between formaldehyde exposure and inflammatory response pathways.
10 Protein Function Prediction via Analysis of Interactomes (Elena Nabieva and Mona Singh).
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