Rigid-body docking - Studying the interactome
However, unlike a simple search engine, Psychic is able to crawl up and down the molecular 'interactome
' to determine the upstream and downstream genes that interact with the gene you've searched for.
Second, DISC1 appears to act as a coordinating scaffold protein that interacts with a huge set of proteins (the DISC1 interactome
), which include APP, Dixdc1, LIS1, NDE1, NDEL1 (for neuronal migration), (75),(76) Grb2, Girdin, PDE4B, FEZ1, several RNA-binding proteins (for signaling and trafficking), (74),(77),(78) Kalirin-7, and TNIK (for glutamatergic synapse function).
cytoHubba: identifying hub objects and sub-networks from complex interactome
. BMC Syst Biol.
Crosstalk between apoptosis and autophagy within the Beclin 1 interactome
. EMBO J.
A map of the interactome
network of the metazoan C.
The $2 million, five-year project, "Cyanobacterial Bloom Microbial Interactome
as a Model for Understanding Biogeographical and Seasonal Patterns in Functional Biodiversity," is supported by the National Science Foundation.
A human interactome
in three quantitative dimensions organized by stoichiometries and abundances.
Recently, the same interactome
approach was used to demonstrate the partners of T.
The metabolic interactome
of CA IX determined using the proximity-dependent biotinylation proteomic approach, recently, revealed a novel role of this isoform in tumor migration and invasion .
Mann, "The phosphotyrosine interactome
of the insulin receptor family and its substrates IRS-1 and IRS-2," Molecular & Cellular Proteomics, vol.